TYMLOS is indicated for the treatment of postmenopausal women with osteoporosis at high risk for fracture defined as a history of osteoporotic fracture, multiple risk factors for fracture, or patients who have failed or are intolerant to other available osteoporosis therapy. In postmenopausal women with osteoporosis, TYMLOS reduces the risk of vertebral fractures and nonvertebral fractures.


Dosing & storage

For postmenopausal women with osteoporosis and a history of osteoporotic fracture, TYMLOS offers patient-administered dosing.1

TYMLOS was designed with patients in mind

Recommended dosage and administration1

Prefilled Tymlos injection pen
Prefilled Tymlos injection pen

30 doses per pen;
80 mcg SC injection once daily

No refrigeration after the first dose

Taken with or without food

Self-administered through a disposable,
5- to 8-mm, 31-gauge needle*

  • The safety and efficacy of TYMLOS have not been evaluated beyond 2 years of treatment. Use of the drug for more than 2 years during a patient’s lifetime is not recommended
  • Patients should receive supplemental calcium and vitamin D if dietary intake is inadequate
  • SC injection into the periumbilical region of the abdomen
  • Rotate injection site every day and administer at approximately the same time every day
  • Administer the first several doses where the patient can sit or lie down, if necessary, in case symptoms of orthostatic
    hypotension occur
*Pen needles are not included and may require a separate prescription in some states.


Storage and handling1

TYMLOS is a once-daily injection that goes where your patients go1

After first use, TYMLOS can be stored for up to 30 days without refrigeration (between 68°F and 77°F), unlike Forteo®, which should be stored under refrigeration at all times.1,2

Before first use

Store in a refrigerator between 36°F and 46°F (2°C and 8°C) at all times.

Do not freeze or subject to heat.

After first use

Store for up to 30 days without refrigeration at a temperature between 68°F and 77°F (20°C and 25°C).

Do not freeze or subject to heat.

Store with pen cap on.

Do not store with needle attached.

Resources are available to help your patients learn how to use the TYMLOS pen

Clinical Educator Network

Injection training is provided through our Clinical Educator Network, which helps patients with a prescription understand how to use the pen and self-inject, and supports them as they start and stay on TYMLOS, as directed by you.

Step-by-step video

See a step-by-step video with instructions for use for patients.

References: 1. TYMLOS [package insert]. Boston, MA: Radius Health, Inc. 2. Forteo [prescribing information]. Indianapolis, IN: Lilly USA, LLC.